Kefir 1. 7 Day Diet Smoothie. I haven’t been posting a lot of recipes this week because my husband and I started the 1. Day Diet on Monday. Mike Moreno recommends is kefir (my husband keeps thinking that I am saying “cat fur.”) . Dukan Diet Recipes and Cook. Bookrecipes for people doing Medifastrecipes for people doing Dukan Dietrecipes for people doing Lean. The newest edition of the best-selling 17 Day Diet by Mike Moreno, MD, promises to help you rev up your fat-burning metabolism, shed pounds, and build healthy new. Gainsrecipes for people doing Nutrisystemrecipes for people doing HCG Dietrecipes for people doing P9. Xrecipes for people doing 1. Day Dietdiet recipes for people on Weight Watchers. Disclaimer: My 17 Day Diet Blog is in no way affiliated with Dr. All information presented on this website is for informational purposes only. Our complete list of over 600 nutritionist reviewed diets arranged in alphabetical order. Choose the diet plan that best fits your goals and lifestyle. The followers of the 17 Day Diet by Dr Mike Moreno can expect fast weight loss of up to 10-12 pounds per week in 17 days with permanent results. The 17 Day Diet was developed by Dr. Michael Moreno who is a practicing family physician in San Diego, CA. The 17 Day Diet consists of three cycles lasting 17. WebMD Site Map - Diet & Weight Management Articles. Diet Myth or Truth: Fasting Is Effective for Weight Loss LIVE with Kelly Recipes. Search our Recipe Finder to find delicious dishes for your kitchen! THE # 1 BESTSELLING DIET! Mike Moreno first published The 17 Day Diet in 2010, millions of people have lost weight using his fast, safe, and extremely. Here's a day of typical meals on a 1,500-calorie Mediterranean diet from Oldways. 6 ounces Greek yogurt topped with 1/2 cup strawberries and.
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TIP #5: YOU DON’T HAVE TO STARVE YOURSELF OR COUNT CALORIES TO LOSE WEIGHTA plate of real food . So next time you feel hunger pangs, stop depriving yourself and fill up on real food, instead. TIP #6: LISTEN TO YOUR BODY & EAT WHEN YOU’RE HUNGRYWhen you are hungry, your body doesn. If you feed it foods that are nutrient- poor, your brain and body will never really feel totally satisfied. The key is to feed yourself real and fresh whole foods that are high in nutrients and satiate your hunger. On The Wild Diet, you simply eat when you. So when eating out, make it a special event, take your time, and enjoy your feast. Order several dishes family style for everyone to try and share . You know, for chocolate emergencies! Why The Wild Diet Is #1 In America. Here. He finished at 2. So Kurt lost an astounding 2. The Wild Diet, while eating delicious food and using proven fat loss techniques, like intermittent fasting. So always keep this in mind – lean muscle is the most important tool you have to boost your metabolism and burn more fat. Kurt wasn. He did quick, functional workouts at home – like kettlebell swings and lifting water jugs – to maintain his lean muscle mass. And we used The Wild Diet. Kurt lost nearly double the amount of body fat as any other contestant on the show. This is a HUGE win for the Wild, high fat / low carb, and Paleo communities!(Want Kurt’s Wild Meal Plans? Get them with the Wild Diet Fat Loss System.)Even more important, Kurt is off all of his prescription medication and feels 2. His blood sugar and blood pressure are in the healthy range, and he! Not to mention, Kurt was able to get these results with limited exercise, just walks outside and a bit of strength training. I share all of this with you to hammer this message home: If you want to lose fat, focus on your diet. If Kurt, Jasmin, Latasha, and Jeff can do it, so can you. Another huge takeaway is that Kurt is still able to enjoy eating pasture- raised bacon, grass- fed burgers, and even our famous cheesecake to drop fat while eating outrageously good food. This ain. You really can be happy and healthy at the same time. Can you lose 2. 0 pounds in 4. FOR A LIMITED TIME: Get The Wild Diet 3. Day Fat Loss System for $2. OFF! The Answer: Eat Real Food. There. Diabetes and cancer are rampant, health care costs are increasingly crippling our economy, and 8- year- old children are weighing in at 3. Clearly, something isn. We really can just look back a generation or two. Our grandmothers knew that processed foods, namely carbohydrates like grains, starch, and sugar, make us fat. And when our grandmothers bought food, it was usually local, organic, and free of most chemicals. Alas, those days have passed. As Alfred Newman quipped in Mad Magazine. You may have seen it featured on People, NPR, or getting Kurt Morgan to drop 5. ABC’s hit show My Diet Is Better Than Yours. By focusing on simple, fresh, ingredients and satisfying fats like butter and avocado, The Wild Diet helps your body shift out of fat- storing mode to burn fat as its main fuel source (hence the pun, “Fat- Burning Man”). By upgrading the quality of their diet, thousands of people across the world have dropped 2. The secret to great health simply getting back to our wild roots and enjoying real, natural foods grown on a farm and not in a factory. Many other trainers and experts tell you that you need to eat diet food that tastes like cardboard if you want to lose weight. I’m going to tell you the exact opposite. The Wild Diet proves that it’s possible to get in best shape of your life while eating delicious foods like chicken parmesan, bacon cheeseburgers, and even chocolate pudding. If you want to know how to burn more fat by indulging in incredible meals and exercising less, it’s time to treat yourself to The Wild Diet. Why Does The Wild Diet Lead to Fat Loss and Better Health? Simply, The Wild Diet suggests that we take a deep breath and start eating real food again. It urges you to eat the highest quality food you can find and afford. Truth be told . And “popular Paleo” today often puts meats at the front and center of every meal. The Wild Diet, however, shows you how to improve your health, drop fat, and boost energy by making plant- based foods more than half your plate. We once had access to an immense variety of seasonal foods from small, local sources. Now we have access to very few varieties of very few foods from a massive industrial system often thousands of miles from where we live. It. As humans, it’s time to get back to our roots. GMO’s are creepy, artificial flavors are horrifying, and selective breeding has unleashed some freakish foodstuffs upon the general public. If selective breeding can do this to a wolf, imagine what they can do to a tomato. Monoculture is destroying the land, generating obscene wealth for a select few, and producing . But the benefits for the health of our bodies and the land we inhabit are undeniable. Here’s a small example of what you eat when you don’t pay attention? Chew on this: secretions from the anal glands of beavers produce a bitter, smelly, orange- brown substance known as castoreum that is used extensively in vanilla and raspberry flavoring. I hope you like beaver butt. The Wild Diet is a Paradigm for Making Healthy Decisions. The Wild Diet is not a dietary bootcamp; it is a template for making healthy eating and lifestyle decisions. But as a rule, the closer you can get to eating plants and animals that would thrive in their wild and natural habitat, the better. Eat plants and animals that were recently alive and well. Heirloom and heritage plants and animals are in themselves healthier as a result more nutritious then their industrial counterparts. Imagine grain is expensive, hard physical work is necessary, and sweets are a treat. Here are a few of my favorites. These folks have lost weight, reduced body fat, and even improved their breathing by transforming their bodies with delicious real food. The following success stories are from regular people who want to help get the word out ! You can literally turn Twinkies into fingernails.” – Abel James“Ignorance isn. The Wild Diet flies in the face of the outdated advice touted by health and wellness . In a sea of marketing hype, Abel James is a powerful and authentic voice that speaks the truth. Abel James shows you how to optimize your workout, diet, and habits to take your health back into your own hands. Abel rocks a chiseled 6 pack and makes it look easy. As the owner of a 1- pack, I marvel at his lean body mass! There’s a reason Abel. Abel has done his research, and his book shows you how to apply it to your life in a very realistic way. This book will change the way you look at food and exercise. More importantly, this book can help you take control of your life. He gives the health movement a personal voice that is fresh, approachable, and knowledgeable. In his book, The Wild Diet, Abel shares his own journey losing 2. By focusing on not just what you eat, but how you eat it, Abel gives a unique perspective on how to think about our diet. Instead, The Wild Diet shows you how to lose fat while satisfying your personal cravings. Somehow I landed on a podcast called “The Fat Burning Man Show.” The host, Abel James, was telling his story and it sounded like he had peaked at my diary. Everything he spoke about resonated with me. I began incorporating the principals of The Wild Diet into my own life and fifty pounds later, I’m a different man. I can tell you that Abel is the real deal. He lives The Wild Diet. The Wild Diet isn’t the latest fad diet book designed to line the author’s pockets only to regurgitate the same old, tired eat less and exercise more mantra. It’s a comprehensive, no nonsense guide to healthy living. It’s packed full of common sense that our grandparents or great- grandparents knew but somehow we’ve forgotten. Abel has re- discovered these truths and he shares them all right here in this book. Speaking as a busy mom, these recipes not only taste great, but can help the whole family get fit as a fiddle!? Don’t forget to leave a review to help me spread the word! Thanks, you rock! Here is where you can get the book: LEARN HOW TO DROP 2. POUNDS IN 4. 0 DAYS WITH REAL FOODDiscover how to drop fat with chocolate, bacon, and cheesecake. Plus: learn the 3 worst foods you should NEVER eat and the 7 best exercises for rapid fat loss. Click below to to claim your FREE gift ($1. Quick Tips to Get Started on The Wild Diet. An error occurred while setting your user cookie. 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The RDA is the amount of a nutrient you need to meet your basic nutritional requirements. In a sense, it’s the minimum amount you need to keep from getting sick . For a 5. 0- year- old woman who weighs 1. But use of the RDA to set daily protein targets has actually caused a lot of confusion. The summit was organized and sponsored by beef, egg, and other animal- based food industry groups, but it also generated a set of scientific reports that were independently published a special supplement to the June issue of the American. Journal of Clinical Nutrition (AJCN). Protein: Is more better? For a relatively active adult, eating enough protein to meet the RDA would supply as little as 1. In comparison, the average American consumes around 1. The Protein Summit reports in AJCN argue that 1. In fact, the reports suggest that Americans may eat too little protein, not too much. The potential benefits of higher protein intake, these researchers argue, include preserving muscle strength despite aging and maintaining a lean, fat- burning physique. Some studies described in the summit reports suggest that protein is more effective if you space it out over the day’s meals and snacks, rather than loading up at dinner like many Americans do. Based on the totality of the research presented at the summit, Rodriguez estimates that taking in up to twice the RDA of protein “is a safe and good range to aim for.” This equates roughly to 1. Liquid Egg Whites 1 Litre Carton; Premium Chicken Breast Fillets - 5kg; 10 x 6-7oz Matured British Rump Steaks; Free Range Whey Protein 85 Concentrate. Weight Loss Tips, Diet and Fitness advice for a healthy weight loss.That range fits nicely into the recommendation from the current Dietary Guidelines for Americans that we get 1. What should you do? Research on the optimal amount of protein to eat for good health is ongoing, and is far from settled. The value of high- protein diets for weight loss or cardiovascular health, for example, remains controversial. Before you start packing in more protein, there are a few important things to consider. For one, don’t read “get more protein” as “eat more meat.” Beef, poultry, and pork (as well as milk, cheese, and eggs) can certainly provide high- quality protein, but so can many plant foods . The table below provides some good sources of protein. It’s also important to consider the protein “package” .
Aim for protein sources low in saturated fat and processed carbohydrates and rich in many nutrients. One more thing: if you increase protein, dietary arithmetic demands that you eat less of other things to keep your daily calorie intake steady. The switches you make can affect your nutrition, for better or for worse. For example, eating more protein instead of low- quality refined carbohydrates, like white bread and sweets, is a healthy choice . Some studies support it, some studies don’t.”Good sources of protein. Food. Protein (grams)3 ounces tuna, salmon, haddock, or trout. Greek yogurt. 17. How To Lose Weight In Just 7 Days. The GM Diet Plan: How To Lose Weight In Just 7 Daysglendon. April 3, 2. 01. 7. Your colleagues, family members, or best friends have uttered these words with great anxiety, concerned about their bulging waistline. Everyone is always in search of that one magical diet that will get them fast results. But out of the thousands of diets available out there, how do you know what really works and what doesn? And do any of them promise results in just seven days? A- Z Of The GM Diet. What Is The GM Diet? The General Motors diet has been around since 1. It was originally developed by. It was designed to increase workforce productivity by making the workers healthier. Results of the diet were impressive ! The workers experienced increased efficiency, confidence, and higher energy. The diet was deemed a great success. Probably the biggest reason millions of people swear by the GM diet is because it. There are no complicated ingredients or great demands on a person. For this reason, we recommend GM diet for you. Let’s see how this diet works to burn the stored fat. Back To TOCHow Does The GM Diet Plan Work? The plan focuses on limiting your weekly diet to eating fruits, vegetables, brown rice, and chicken. The diet focuses on consuming a combination of complex carbohydrates, low- calorie vegetables, and fruits, and increasing water intake to help achieve a weight loss of up to 1. Below is a day- to- day guide for anyone who wants to follow the GM diet. Caution: Always consult a doctor before starting on a diet regimen. Back To TOCThe GM Diet Plan. GM Diet Plan Day 1. You Will Need. A variety of fruit . There are no restrictions on when you can eat. Watermelons and cantaloupes are the recommended fruits as they are high in fiber. Other healthy choices include papaya, apples, and oranges. You must also consume 8. At no point is it advised to starve. If you feel hungry, you can grab some fruits and satisfy your craving. A Schedule You Could Follow. Breakfast. 8 am – 9 am)A regular sized apple with a glass of water. Brunch(1. 1 am . They are also low in fat. In addition, the high amount of water intake will flush out the toxins and prepare your body for the next six days of dieting. There are some foods that may hinder your weight loss. Here is a list of foods that you should avoid. Foods To Avoid. Vegetables ? Don’t worry, we have a food substitutes list ready for you. Substitutes. Apple . Melons are also a good choice; you can lose up to three pounds by the end of day 1. Eating good and less will help you to a certain extent. To activate the lipid mobilization, you have to exercise. Here is a list of basic exercises that you can start with. Exercises. Since you will be on only fruits and water, do not perform rigorous exercises. You may do these exercises early in the morning or in the evening after office or school. Here is your customized exercise plan for Day 1. Arm circles . Please consult your trainer or doctor. How You Will Feel By The End Of Day 1. Day 1 will be comparatively easy since the monotony of eating fruits and veggies has not crept in yet. If you stick to the diet plan and exercise routine, you will feel active, energetic, and great about yourself by the end of Day 1. Ready for Day 2? Back To TOCGM Diet Plan Day 2. You Will Need. An assortment of vegetables. Some of the healthiest options would be carrots, beans, tomatoes, cucumbers, lettuce, and cabbage. What You Have To Do. You have to follow a vegetable- only meal plan on the second day. You can cook the vegetables to make them palatable, or consume them raw. Care should be taken while preparing the vegetables as oil is not allowed. So, forget deep frying your favorite potatoes or eating chips. You can have the vegetables whenever you feel hungry. Flavorings like olive oil or butter can be used sparingly, only if absolutely required. A Schedule You Could Follow. Breakfast. 8 am – 9 am)A boiled potato. You can also add a teaspoon of low- fat butter for flavor. Brunch(1. 1 am . Potatoes have carbohydrates, peas have protein, and carrots and beans are full of fiber and essential vitamins (2). After the relatively low carb day, this will replenish your carb stores and will energize you for the next day of the diet. It’s all good as long as you avoid the following listed foods. Foods To Avoid. Fruits ? Take a look at the substitute list to break the monotony. Substitutes. Potato ! You can also switch to cabbage soup or tomato soup and have it for lunch or dinner. As long as you stay active, you will keep many obesity- related diseases and heart diseases at bay. Check out the exercise regimen for Day 2. Exercises. A similar exercise routine as Day 1, but a slightly strenuous workout plan to help mobilize the fat. You may do these exercises early in the morning or in the evening after office or school. Surya Namaskar (click here to see the steps to perform Surya Namaskar). Kapalbhati . Please consult your doctor or trainer to know the best yoga asanas for you. How You Will Feel By The End Of Day 2. You may start to feel weak from late afternoon on Day 2. Do not worry, this is normal with most low- calorie diet plans. Your body will not get the usual amounts of carbs and hence will react by making you feel slow and weak. Let’s move on to Day 3 and see what. You could stick to the fruits and vegetables consumed during the first two days. The only foods to avoid are potatoes and bananas. What You Have To Do. On the third day, your body would have almost adjusted to the new diet. After a day of eating just vegetables, fruits will bring a welcome break. It will also combine the benefits of both fruits and vegetables, and provide you with high fiber, nutrient, and protein. Here is the diet plan that you will follow on Day 3 of the GM diet plan. A Schedule You Could Follow. Breakfast. 8 am – 9 am)Half a bowl of cantaloupe or a sliced apple and two glasses of water. Brunch(1. 1 am . Fruits and vegetables provide fiber and nutrients, giving your body what it needs. The variety will also help satisfy your taste buds and break the monotony of the first two days. The water will help flush the toxins out. Certain foods need to be avoided on Day 3 for better weight loss results. Foods To Avoid. Vegetables . You can also drink the GM diet soup for lunch or dinner. A simple and easy to follow exercise regimen will help burn the extra calories. Here is the list of exercises that you should do on Day 3. Exercises. On this day, start with a warm up and move on to some energy expending exercises. You may do these exercises early in the morning or in the evening after office or school. Here is the list of the exercises that will keep you feeling energetic all day long. Arms circles . If you are not comfortable with doing an exercise continuously, take 2- 3 minutes break and then complete the set. Do not perform a particular exercise if you have an old injury. Consult your doctor or trainer to know whether you should do the listed exercises. How You Will Feel By The End Of Day 3. Day 3 will make you feel better again as you will get a good amount of fruit sugar from the fruits and a little amount of carbs from the veggies. Exercising and staying active will also make you feel great. To keep it real, Day 4 is challenging but that’s the whole point here. Get ready for Day 4. Back To TOCGM Diet Plan Day 4. You Will Need. Eight bananas and four glasses of milk. What You Have To Do. The fruit you. It is advised to eat eight bananas over the course of the day. Distribute them among your meal and snack times. Also, consume a big glass of milk, thrice, once each at breakfast, lunch, and dinner. If this gets monotonous, you can also include a bowl of soup. Sounds easy, but let’s not leave room for any error. Here is the Day 4 diet schedule. A Schedule You Could Follow. Breakfast. 8 am – 9 am)Two large bananas and a glass of milk. Brunch(1. 1 am . Half a teaspoon of honey can be added as a sweetener. Lunch (1: 3. 0 pm – 2 pm)A bowl of GM diet soup. Post Lunch Snack(4 pm . They are rich in pectin, which aids digestion. They are also high in potassium and low in salt (3). Milk is a great source of calcium and potassium. It is also fortified with vitamin D that. The following list will help you keep a mental checklist on which foods to avoid on Day 4. Foods To Avoid. Vegetables . You could also include the GM diet soup for both lunch and dinner. Bananas provide a lot of energy. Therefore, exercising early in the morning or in the evening will not make you feel weak. The following exercises will help you mobilize fat and boost your metabolism. Exercises. All those calories from the bananas should be expended so that the energy from the bananas don’t get stored as fat. You may do these exercises early in the morning or in the evening after office or school. Here is the list of exercises that you should do on Day 4. Arms circles . Take the advice of your doctor or trainer before starting the exercises. How You Will Feel By The End Of Day 4. The monotony of eating bananas and milk can make you feel demotivated. You may also experience mood swings. However, drinking enough water, working out, and talking to people who have successfully lost weight by following the GM diet will keep you going. Great job! You have successfully completed Day 4. Now, let’s move on to day 5. Back To TOCGM Diet Plan Day 5. You Will Need. Vegetarians can opt for a cup of brown rice. Non- vegetarians can have a lean protein source like chicken breast or fish. You will also need to consume six large tomatoes. What You Have To Do. This day is a feast compared to what you consumed on the first four days. Vegetarians can have a serving of brown rice for lunch. It is recommended that a minimum amount of oil be used while cooking. To combat the high amount of uric acid your body will be producing, you must increase your daily water intake to 1. For Non- vegetarians. Eat 5. 00gms of skinless chicken baked or lightly fried and don. Here is the Day 5 diet plan to make it more easy for you to follow. A Schedule You Could Follow. Athleat Online Grass Fed Meat Store. It’s quite simple and Athleat makes the process even simpler by providing the quality products that allow athletes to thrive, not just survive. You don’t short- change yourself when training, so why do it in the kitchen. Drummond Company, Inc. Being a leader means an unyielding commitment to provide our clients with the very best in quality and service. In addition to coal, Drummond is the largest merchant coke producer in the U. Plotter Paper for Wide Format Inkjet. 20lb Inkjet CAD Bond 36 x 150 Foot Roll - 4 Roll Carton - FREE SHIPPING. The Rock's Tearful Surprise! Life and career Early life. 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Amphetamines were used to increase concentration levels and mental alertness in soldiers, while they decreased symptoms of fatigue and hunger. This is what primarily led to researchers in the United States studying the effects of amphetamines after the conclusion of the war. Corporations also saw potentially huge markets if drugs based on amphetamines were made available to the general public. Since 2. 01. 2, the FDA has approved around four weight loss products, but phentermine has continued to be remain the market leader in this segment. As long as the price of phentermine remains relatively low when compared to its competition, the drug will continue to be the preeminent drug in the market. A brief history of phentermine. Physicians recommend 25 - 35 grams of daily fiber intake for optimal health and to assist in effective weight loss. Quick Weight Loss Centers has an exclusive selection of herbal weight loss aids & vitamin supplements. In the United States, phentermine was approved by the Food and Drug Administration (FDA) in 1. The first version of this drug was phentermine resin and the FDA approved its usage for the short- term treatment of obesity. Phentermine was one of the first commercially available appetite suppressants in the United States. Due to yet understood and potentially dangerous side effects, the drug was limited to a ninety day administration period when it was released to the public in 1. The FDA wanted more research to be carried out on the drug before it was prescribed to patients for an indefinite period of time. Phentermine managed to build up its reputation as a generic drug that effectively combated obesity. In the 1. 97. 0s, the drug was sold as phentermine hydrochloride with HCL (hydrochloric acid) becoming a part of the drug's chemical composition. When it was released in this form, it did not have any limited administration period. Phentermine hydrochloride is typically sold in the form of 3. The effect of this is equivalent to about 3. The normal adult dosage is generally one tablet per day but this is often tailored to the needs of individual patients. In some cases, it is more appropriate to consume two dosages of 1. Phentermine is normally not suitable for pediatric patients, but this hasn't stopped physicians from prescribing them to anyone over the age of 1. Phentermine hydrochloride is similar to white crystalline powders. The substance is highly soluble in both water and alcohol. Some of the ingredients in the substance include starch, isopropyl alcohol, titanium dioxide, proplyene glycol, and ethyl alcohol. The drug was commonly sold as Fastin, which was manufactured by King Pharmaceuticals, when it was first introduced to the market. Phentermine has been marketed under the names adipex, phentrol, sinpet, supremin, umine, panbesy, duromine, weltmine, and suprenza. Phentermine hydrochloride has a long and illustrious history when compared to other weight loss drugs and substances. However, there have been very few if any clinical trials that have been carried out to understand the effects of phentermine hydrochloride on human beings. As phentermine alone has received very little heat from authorities, it has never been the focus of the FDA. However, the combinations of phentermine with fenfluramine and dexfenfluramine were extensively studied in 1. FDA- approved, were getting. This would eventually lead to the removal of Fen- Phen and Dexfen- Phen from the market. Fen- Phen and Dexfen- Phen. In the 1. 97. 0s, phentermine hydrochloride was commonly used in tandem with other drugs to produce a powerful appetite suppressant. Specifically, it was prescribed by numerous physicians along with fenfluramine. Fenfluramine was approved as an anorectic agent by the FDA in 1. This drug would become a part of the infamous Fen- Phen combination, which hit the shelves in the early 1. The Fen- Phen combination was marketed a wonder blend that was highly effective for fat burning and weight loss. The FDA never legally approved this drug combo but that did not stop physicians from prescribing it. Numerous physicians benefited by selling the drugs together and this combination was regarded to be an effective, off- label medication. Phentermine was also used in tandem with dexfenfluramine, the Dexfen- Phen combination. Dexfenfluramine was approved by the FDA in 1. However, the rails began to fall off as this wonder combination was found to have induced negative side effects in its users. The Mayo Clinic findings of 1. Fen- Phen and Dexfen- Phen. In 1. 99. 7, the authors of a report published in the New England Journal of Medicine (NEJM) suggested a link between sustained use of these anorectic agents and mitral valve dysfunction, which is basically a heart valve disease. The paper estimated that in 1. Fen- Phen combination had been prescribed to nearly 2. A 3. 0- year- old woman, who had been using the Fen- Phen for a month, developed heart complications in 1. The Boston Herald published a front page article in her memory in the aftermath of her death in February 1. Multiple patients filed grievance reports at this time, citing the ill effects of Dexfen- Phen and Fen- Phen on their bodies. People all over the country were reporting side effects on a daily basis, putting pressure on the FDA and American Home Products. Patients, who had consumed only fenfluramine and dexfenfluramine, without combining them with phentermine, were also reporting side effects. As these drugs were all FDA- approved, neither combination had ever been tested for safety by the FDA or American Home Products. The Mayo Clinic had reported twenty four separate cases of heart valve disease by the summer of 1. The FDA could no longer sit idle and by September 1. Michael Friedman, who was the FDA's Lead Deputy Commissioner at the time, sent out a press release, publicly condemning fenfluramine and dexfenfluramine. The FDA recommended that consumers should consume neither of the drugs as nearly 3. Mayo Clinic report stated that they were experiencing abnormal heart valve issues. However, phentermine received a stay of execution and continued to be commercially available. What exactly is phentermine and how does it work? Phentermine is a substituted amphetamine based on the amphetamine structure. It is chemically and pharmacologically similar to the other types of drugs that have used as obesity treatment over the years. Phentermine and other drugs of this type are considered to be anorexigenics or anorectics. It is also pharmacologically similar to substances such as methamphetamine (crystal meth), MDMA, ephedrine, and amphetamine itself. The substance is a psychostimulant drug and it possesses hallucinogenic properties. As all amphetamine- based substances are considered to be controlled substances, phentermine is classified as a Schedule IV controlled substance because it apparently possesses a high potential for abuse. The drug should always be taken with extreme precaution and users must never take multiple doses of phentermine as it can be as addictive as crystal methamphetamine and ecstasy. The chemical name of phentermine is 1,1- Dimethyl- 2- phenylethylamine. It is a synthetic organic compound. The chemical formula of phentermine is C1. H1. 5N. The molecular weight of synthesized phentermine is 1. Phentermine is a psychostimulant as it stimulates the central nervous system and elevates blood pressure. This is how it functions as an appetite suppressant. Phentermine is a TAAR1 agonist as it activates TAAR1 in monoamine neurons, thereby facilitating the release of these neurons into the synapse. Phentermine primarily releases norepinephrine from neurons and dopamine & serotonin to a lesser extent. Phentermine is a substance that causes neurons to expunge or maintain levels of a group of neurotransmitters that are called catecholamines. Dopamine and norepinephrine are a part of this group. The drug appears to inhibit reuptake of these neurotransmitters by inhibiting or reversing the reuptake transporters. The drug also inhibits MAO enzymes, which causes a greater amount of neurotransmitters to remain at the synapse. By elevating these catecholamines, experts hypothesize that the drug may have an impact on the brain's leptin levels. Phentermine is believed to raise the brain's leptin levels. The elevation of catecholamines is also believed to halt the chemical messenger neuropeptide Y, a peptide responsible for increasing hunger and fat storage. Phentermine primarily works to reduce obesity by reducing the body's hunger perception. This is mainly done through a cognitive process by working on several nuclei in the hypothalamus section of the brain. The drug also works outside the brain by releasing adrenaline and noradrenaline to ensure that fat cells break down stored fat in the body. Usage and administration. Phentermine consumption must always be accompanied by weight reduction- based exercises, reduced intake of calories, and suitable behavioral modification, all of which must be based on an individual’s level of weight. Ideally, phentermine should be consumed in the morning an hour or two before the first meal of the day. |
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